Atrasentan Impurity 169 CAS 1059043-50-3
| CAS No. | 1059043-50-3 |
| Molecular Formula | C33H46N2O6 |
| Molecular Weight | 566.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Atrasentan Impurity 169.
CATO supplies Atrasentan Impurity 169 (CAS 1059043-50-3), a pharmacopoeial impurity reference standard (molecular formula C33H46N2O6, MW 566.74 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Atrasentan Impurity 169 (C33H46N2O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 566.74 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C33H46N2O6 |
| Molecular Weight | 566.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Atrasentan Standards
- Atrasentan Impurity 101 (CAS 1059052-04-8)
- Atrasentan Impurity 112 (CAS 1059754-98-1)
- Atrasentan Impurity 140 (CAS 1058349-19-1)
- Atrasentan Impurity 152 (CAS 1058404-01-5)
- Atrasentan Impurity 154 (CAS 1058404-07-1)
- Atrasentan Impurity 168 (CAS 1059043-43-4)
- Atrasentan Impurity 173 (CAS 1059051-91-0)
- Atrasentan Impurity 174 (CAS 1059051-97-6)
Recommended Standards
- Atrasentan Impurity 175 (CAS 1059051-98-7)
- Atrasentan Impurity 181 (CAS 1073590-82-5)
- 3,6,9,12,15,18,21,24-Octaoxaheptatriacontanoic acid (CAS 66161-61-3)
- 4,4'-Bis(2,2-di-p-tolylvinyl)-1,1'-biphenyl (CAS 135804-06-7)
- Capecitabine Impurity 37 (CAS CATO-C4X-102437)
- Salbutamol Impurity 138 Trifluoroacetic Acid (CAS CATO-C4X-1176138)
- Imatinib Impurity 50 (CAS CATO-C4X-106850)
- 1-(Pyridin-3-yl)butane-1,3-dione (CAS 3594-37-4)
- (Z)-n'-hydroxy-3-methylthiophene-2-carboximidamide (CAS 878649-98-0)
- 3-Bromo-4-methylphenol (CAS 60710-39-6)
- 4-Hydroxy-2-isobutyl-8-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 64321-90-0)
- Octan-2-amine hydrochloride (CAS 24301-94-8)
- Ponatinib Metabolite AP-24567 N-Glucuronide (Amadori Rearrangement Product) (CAS CATO-C4X-226926)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com