5-Chloro-1-(4-fluorophenyl)-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole CAS 106516-07-8
| CAS No. | 106516-07-8 |
| Molecular Formula | C19H16ClFN2 |
| Molecular Weight | 326.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-1-(4-fluorophenyl)-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (CAS 106516-07-8) is a high-purity analytical reference standard with the molecular formula C19H16ClFN2 and a molecular weight of 326.80 g/mol.
Structurally, 5-Chloro-1-(4-fluorophenyl)-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (C19H16ClFN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 326.80 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16ClFN2 |
| Molecular Weight | 326.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-(4-(3-Chloro-4-methoxyphenyl)-2-(dimethylamino)thiazol-5-yl)acetic acid (CAS 1443286-16-5)
- 6-Chloro-4'-(ethylsulfonyl)-2'-methoxy-[1,1'-biphenyl]-3-ol (CAS 1614246-64-8)
- 4-Chloro-3-ethoxy-N-(pyridin-3-ylmethyl)benzenesulfonamide (CAS 691380-73-1)
- 4-Chloro-3-propoxy-N-(pyridin-3-yl)benzenesulfonamide (CAS 879049-43-1)
- 3-(6-Chloro-2-methylsulfanyl-pyrimidin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester (CAS 1261232-45-4)
- 3-Chloro-6-((S)-pyrrolidin-3-yloxy)-pyridazine hydrochloride (CAS 1261233-44-6)
- [1-(6-Chloro-pyrimidin-4-yl)-piperidin-3-yl]-methyl-carbamic acid tert-butyl ester (CAS 1261233-51-5)
- (2-Chloro-8-methyl-quinolin-3-ylmethyl)-(4-methoxy-benzyl)-amine (CAS 606095-52-7)
Recommended Standards
- Nintedanib Impurity 164 (CAS CATO-C4X-1814164)
- Fenirofibrate-d6 (CAS 1189423-29-7)
- Rebamipide Impurity 4 (CAS 100342-53-8)
- Diazepam Impurity 7 (CAS 28910-89-6)
- 2-bromo-6-methoxy-4-{[(1-methyl-1H-pyrazol-4-yl)amino]methyl}phenol hydrochloride (CAS 1208639-77-3)
- Methyl Methanethiosulfonate-d3 (CAS 55800-37-8)
- 959617-49-3 1,5-Naphthyridine-3-carbaldehyde DTXSID50678410 (CAS 959617-49-3)
- Allyl(chloromethyl)dimethylsilane (CAS 33558-75-7)
- 3-Amino-N-Boc-9-azabicyclo[3.3.1]nonane (CAS 202797-03-3)
- Flavokermes AcidDISCONTINUED (CAS 18499-84-8)
- Aprepitant Impurity 73 (CAS CATO-C4X-114173)
- 2-((2-Aminoethyl)amino)pyrimidine-5-carboxylic acid (CAS 1017412-37-1)
- Methyl 1-[(4-methylbenzene)sulfonyl]azetidine-3-carboxylate (CAS 1820684-87-4)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com