Hydrocortisone Impurity 44 CAS 106597-71-1
| CAS No. | 106597-71-1 |
| Molecular Formula | C46H62O12 |
| Molecular Weight | 806.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Hydrocortisone Impurity 44 (CAS 106597-71-1), a pharmacopoeial impurity reference standard (molecular formula C46H62O12, MW 806.98 g/mol) used for the identification and quantification of trace impurities in APIs.
Hydrocortisone Impurity 44 (C46H62O12) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C46H62O12 |
| Molecular Weight | 806.98 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
Related Hydrocortisone Standards
- Hydrocortisone impurity 42 (CAS CATO-C4X-140142)
- Hydrocortisone 21 Phosphate Dimer (CAS 20513-23-9)
- Hydrocortisone EP Impurity N (CAS CATO-C4X-140114)
- Hydrocortisone Impurity 74 (CAS CATO-C4X-140174)
- Hydrocortisone Impurity 54 (CAS CATO-C4X-140154)
- Hydrocortisone Impurity 66 (CAS CATO-C4X-140166)
- Hydrocortisone Impurity 52 (CAS CATO-C4X-140152)
- Hydrocortisone 21-Octanoate (CAS 6678-14-4)
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