Palbociclib Impurity 2 CAS 1072-97-5
| CAS No. | 1072-97-5 |
| Molecular Formula | C5H5BrN2 |
| Molecular Weight | 173.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Palbociclib Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Palbociclib Impurity 2 (CAS 1072-97-5, C5H5BrN2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrile group, bromine substitution, Palbociclib Impurity 2 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 173.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C5H5BrN2 |
| Molecular Weight | 173.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Palbociclib Standards
- Palbociclib Impurity 32 (CAS 1082876-26-3)
- Palbociclib Impurity 175 (CAS CATO-C4X-1125175)
- Palbociclib Impurity 181 (CAS 2601903-88-0)
- Palbociclib Impurity 44 (CAS CATO-C4X-112544)
- Palbociclib Impurity 42 (CAS 51534-87-3)
- Palbociclib Impurity 174 (CAS CATO-C4X-1125174)
- Palbociclib Impurity 88 (CAS 868591-58-6)
- Palbociclib Impurity 60 (CAS 28564-83-2)
Recommended Standards
- 4-Bromophenol (CAS 106-41-2)
- 2-Amino-3-bromopyridine (CAS 13534-99-1)
- 3-Bromophenol (CAS 591-20-8)
- Phloroglucinol Impurity 15 (CAS 95-56-7)
- Olanzapine Embonate Monohydrate EP Impurity F (CAS CATO-C4X-117863)
- Methylphenidate EP Impurity F (CAS 7251-52-7)
- Cefixime Impurity 9 (CAS 80544-17-8)
- 2,6-Dichloro-4-cyanobenzoic acid (CAS 1258298-05-3)
- methyl 2-(5-amino-4-chloro-2-methylphenoxy)acetate (CAS 1334146-96-1)
- 3-Bromo-4-(bromomethyl)thiophene (CAS 40032-80-2)
- tert-butyl rel-(2S)-2-methyl-3-[(4R)-4-methyl-2,5-dioxo-imidazolidin-4-yl]propanoate (CAS 1957284-34-2)
- LCZ-696 Impurity 87 (CAS 2061992-11-6)
- 4-(2-Aminopropanoyl)-1lambda6-thiomorpholine-1,1-dione hydrochloride (CAS 1251922-66-3)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com