Minocycline EP Impurity F CAS 1075240-33-3
| CAS No. | 1075240-33-3 |
| Molecular Formula | C24H29N3O8 |
| Molecular Weight | 487.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 487.50 g/mol gives Minocycline EP Impurity F distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Minocycline EP Impurity F (CAS 1075240-33-3) is a certified pharmaceutical impurity reference standard with the molecular formula C24H29N3O8 and a molecular weight of 487.50 g/mol.
The molecular framework of Minocycline EP Impurity F (C24H29N3O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Minocycline EP Impurity F meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H29N3O8 |
| Molecular Weight | 487.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
Related Minocycline Standards
- Minocycline Impurity 54 (CAS CATO-C4X-169954)
- Minocycline Impurity 31 (CAS CATO-C4X-169931)
- Minocycline Dehydro Impurity (CAS CATO-C4X-16995)
- Minocycline EP Impurity G (CAS 601455-95-2)
- Minocycline impurity 74 (CAS 17779-50-9)
- Minocycline impurity 76 (CAS CATO-C4X-169976)
- Minocycline Impurity 26 (CAS 149934-16-7)
- Minocycline Impurity 33 (CAS CATO-C4X-169933)
Recommended Standards
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- ((2R,3S,5R)-5-(5-Fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl palmitate (CAS 96733-83-4)
- 15-(tert-Butyl)tetradecahydrobenzo[b][1,4,7,10,13]pentaoxacyclopentadecine (CAS 17454-49-8)
- Levalbuterol Impurity 3 (CAS CATO-C4X-22593)
- 5-(2-Cyclobutylpyridin-4-yl)-4-methylthiazol-2-amine (CAS 1395492-60-0)
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