Azilsartan Impurity 51 CAS 139481-38-2

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.139481-38-2
Molecular FormulaC27H25N3O6
Molecular Weight487.50 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Azilsartan Impurity 51 CAS 139481-38-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 487.50 g/mol gives Azilsartan Impurity 51 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Azilsartan Impurity 51 (CAS 139481-38-2), a pharmacopoeial impurity reference standard (molecular formula C27H25N3O6, MW 487.50 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Azilsartan Impurity 51 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 487.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC27H25N3O6
Molecular Weight487.50 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)17.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1996
Nitrogen Atoms3

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