Minocycline Impurity 33 CAS CATO-C4X-169933
| CAS No. | CATO-C4X-169933 |
| Molecular Formula | C22H24N4O8 |
| Molecular Weight | 472.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Minocycline Impurity 33.
Minocycline Impurity 33 (CAS CATO-C4X-169933) is a certified pharmaceutical impurity reference standard with the molecular formula C22H24N4O8 and a molecular weight of 472.45 g/mol.
Structurally, Minocycline Impurity 33 (C22H24N4O8) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 472.45 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Minocycline Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24N4O8 |
| Molecular Weight | 472.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Minocycline Standards
- Minocycline Impurity 57 (CAS CATO-C4X-169957)
- Minocycline Impurity 66 (CAS CATO-C4X-169966)
- Minocycline impurity 74 (CAS 17779-50-9)
- Minocycline impurity 76 (CAS CATO-C4X-169976)
- Minocycline Impurity 59 (CAS CATO-C4X-169959)
- Minocycline-d7 (Major) (CAS CATO-CCAD302583)
- Minocycline-D6 (CAS CATO-C1028952)
- Minocycline Impurity 31 (CAS CATO-C4X-169931)
Recommended Standards
- N-Nitroso Minocycline EP Impurity C (CAS 28698-93-3)
- Folic acid impurity 58 (CAS CATO-C4X-139558)
- N-Nitroso Minocycline impurity 80 (CAS CATO-C4X-169980)
- Folic Acid Impurity 35 (CAS 2311-81-1)
- Dopamine Impurity 72 Dihydrochloride (CAS 918419-42-8(free base))
- Norfloxacin Impurity 63 (CAS 106847-42-1)
- Entecavir Impurity C66 (CAS 156422-39-8)
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