Hydroxychloroquine Impurity 30 CAS 1077-74-3
| CAS No. | 1077-74-3 |
| Molecular Formula | C9H5Cl2NO |
| Molecular Weight | 214.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Hydroxychloroquine Impurity 30.
Hydroxychloroquine Impurity 30 (CAS 1077-74-3), molecular formula C9H5Cl2NO and molecular weight 214.05 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Hydroxychloroquine Impurity 30 (C9H5Cl2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 214.05 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Hydroxychloroquine Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5Cl2NO |
| Molecular Weight | 214.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine impurity 87 (CAS CATO-C4X-183587)
- Hydroxychloroquine Impurity N54 (CAS 5448-52-2)
- Hydroxychloroquine Impurity 76 (CAS 91066-18-1)
- Hydroxychloroquine Impurity 19 (CAS 86-47-5)
- Hydroxychloroquine Impurity 57 (CAS 860205-48-7)
- Hydroxychloroquine Impurity 11 (CAS 21617-12-9)
- Hydroxychloroquine EP Impurity G (CAS 86-98-6)
- Hydroxychloroquine Impurity 19 (CAS 23834-01-7)
Recommended Standards
- 2-(Ethylsulfonyl)phenylboronic Acid (CAS 1042443-60-6)
- 2,8-Dichloroquinazolin-4-amine (CAS 1107694-84-7)
- 4,6-Dichloro-2-methylpyrido[3,4-d]pyrimidine (CAS 1029720-75-9)
- 4-Amino-2,5-dichloroquinazoline (CAS 1107695-06-6)
- 3-(2-Fluorophenyl)-N-(2-(2-fluorophenyl)acetyl)propiolamide (CAS 1956385-81-1)
- 5-Methylpyridine-2-boronic acid, mono-lithium salt (CAS 1072946-48-5)
- tert-Butyl 3-methylbut-2-enoate (CAS 22842-54-2)
- 3-Amino-4-cyclobutyl-2-oxobutanamide (CAS 816444-95-8)
- γ-Linolenic ChlorideDISCONTINUED (CAS 54562-14-0)
- (S)-Propafenone (CAS 107381-32-8)
- 3-Iodo-6,7-dimethoxy-2-methylquinolin-4(1H)-one (CAS 1330753-48-4)
- 1-((4-Nitrophenyl)sulfonyl)-1H-1,2,4-triazole (CAS 57777-84-1)
- 4-Iodo-1-(prop-2-yn-1-yl)-1H-pyrazole (CAS 1342001-17-5)
- Macrophage Inhibitory Peptide (CAS 41961-56-2)
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