Hydroxychloroquine Impurity 76 CAS 91066-18-1
| CAS No. | 91066-18-1 |
| Molecular Formula | C11H11ClN2O |
| Molecular Weight | 222.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Hydroxychloroquine Impurity 76 (C11H11ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 222.67 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Hydroxychloroquine Impurity 76 (CAS 91066-18-1), a pharmacopoeial impurity reference standard (molecular formula C11H11ClN2O, MW 222.67 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Hydroxychloroquine Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11ClN2O |
| Molecular Weight | 222.67 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine Impurity 19 (CAS 86-47-5)
- Hydroxychloroquine Impurity 57 (CAS 860205-48-7)
- Hydroxychloroquine Impurity 30 (CAS 1077-74-3)
- Hydroxychloroquine Impurity 19 (CAS 23834-01-7)
- Hydroxychloroquine impurity 87 (CAS CATO-C4X-183587)
- Hydroxychloroquine Impurity N54 (CAS 5448-52-2)
- Hydroxychloroquine Impurity 20 (CAS 630067-21-9)
- Hydroxychloroquine EP Impurity F (CAS 6281-58-9)
Recommended Standards
- Econazole impurity 18 (CAS 24155-45-1)
- Encorafenib Impurity 7 (CAS 2285221-21-6)
- Econazole impurity 17 (CAS 24155-44-0)
- Acetamiprid (CAS 135410-20-7)
- Iodixanol EP Impurity I (CAS CATO-C4X-16639)
- Apalutamide Impurity 117 (CAS CATO-C4X-2749117)
- Benzyl Alcohol Impurity 14 (CAS 19800-47-6)
- Methyl 4-(1-hydroxyethyl)benzoate (CAS 84851-56-9)
- N-Boc-4-(Fmoc-amino)-L-phenylalanine (CAS 114346-31-5)
- 7-Methyl-2,3-dihydrophenanthren-4(1H)-one (CAS 1504-28-5)
- N-(p-Hydroxyphenethyl)-N-(2-bromo-5-hydroxy-4-methoxybenzyl)formamide (CAS 122584-18-3)
- Favipiravir Impurity 11 (CAS 6863-74-7)
- Ethyl 4-cyano-5-(methylthio)thiophene-2-carboxylate (CAS 116170-84-4)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com