N-(4-aminophenyl)-2-chloro-4,5-difluorobenzamide CAS 1087448-65-4

Description

The molecular framework of N-(4-aminophenyl)-2-chloro-4,5-difluorobenzamide (C13H9ClF2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

N-(4-aminophenyl)-2-chloro-4,5-difluorobenzamide (CAS 1087448-65-4), molecular formula C13H9ClF2N2O and molecular weight 282.67 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-aminophenyl)-2-chloro-4,5-difluorobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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