Cariprazine Impurity 43 CAS 1092822-52-0
| CAS No. | 1092822-52-0 |
| Molecular Formula | C20H29Cl2N3O |
| Molecular Weight | 398.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Cariprazine Impurity 43 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Cariprazine Impurity 43 (CAS 1092822-52-0), a pharmacopoeial impurity reference standard (molecular formula C20H29Cl2N3O, MW 398.37 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Cariprazine Impurity 43 (C20H29Cl2N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H29Cl2N3O |
| Molecular Weight | 398.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Cariprazine Standards
- Cariprazine Impurity 26 (CAS CATO-C4X-240826)
- Cariprazine Impurity 27 (CAS CATO-C4X-240827)
- Cariprazine Impurity 65 (CAS CATO-C4X-240865)
- Cariprazine Impurity 46 (CAS CATO-C4X-240846)
- Cariprazine Impurity 67 (CAS CATO-C4X-240867)
- Cariprazine Impurity 25 (CAS CATO-C4X-240825)
- Cariprazine Impurity 18 (CAS CATO-C4X-240818)
- Cariprazine Impurity 63 (CAS CATO-C4X-240863)
Recommended Standards
- Nifedipine impound 37 (CAS CATO-C4X-141037)
- N-[9-(2-Hydroxyethyl)-9H-carbazol-3-yl]-2-(trifluoromethyl)benzamide (CAS 1195786-61-8)
- Nifedipine Impurity 14 (CAS 108139-78-2)
- N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(trifluoromethyl)benzamide (CAS 149981-36-2)
- Ibrutinib Impurity 169 (CAS CATO-C4X-1064169)
- Lapatinib Impurity 46 (CAS 320337-10-8)
- Lemborexant impurity 10 (CAS CATO-C4X-304210)
- 8-Chloropyrido[2,3-b]pyrazin-3(4H)-one (CAS 1838674-97-7)
- Dysprosium(III) acetate hydrate (CAS 304675-49-8)
- 1-(2-methylpentyl)piperidin-4-one hydrochloride (CAS 1803605-15-3)
- Relugolix Impurity 92 (CAS CATO-C4X-242992)
- 879-18-5 1-Naphthalenecarbonyl chloride 1-Naphthoyl chloride 1-(Chlorocarbonyl)naphthalene EINECS 212-903-9 1-Naphthoic acid chloride alpha-Naphthoyl chloride NSC 9841 (CAS 879-18-5)
- N-(2-chlorophenyl)-1H-pyrazole-3-carboxamide (CAS 305346-16-1)
- D-allo-Thr5-Semaglutide (CAS CATO-C4X-2226243)
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