Cariprazine Impurity 67 CAS CATO-C4X-240867
| CAS No. | CATO-C4X-240867 |
| Molecular Formula | C17H18Cl2N2O2S |
| Molecular Weight | 385.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Cariprazine Impurity 67 (CAS CATO-C4X-240867), a pharmacopoeial impurity reference standard (molecular formula C17H18Cl2N2O2S, MW 385.31 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Cariprazine Impurity 67 (C17H18Cl2N2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cariprazine Impurity 67 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H18Cl2N2O2S |
| Molecular Weight | 385.31 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Cariprazine Standards
- Cariprazine Impurity 25 (CAS CATO-C4X-240825)
- Cariprazine Impurity 46 (CAS CATO-C4X-240846)
- Cariprazine Impurity 27 (CAS CATO-C4X-240827)
- Cariprazine Impurity 65 (CAS CATO-C4X-240865)
- Cariprazine Impurity 26 (CAS CATO-C4X-240826)
- Cariprazine Impurity 43 (CAS 1092822-52-0)
- Cariprazine Impurity 13 (CAS 1698050-46-2)
- Cariprazine Impurity 52 (CAS CATO-C4X-240852)
Recommended Standards
- N-Phenyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)aniline (CAS 2096338-53-1)
- 1,3-Dibenzyldihydro-1H-selenolo[3,4-d]imidazole-2,4-(3H,3aH)dione (CAS 1185143-93-4)
- 4-Nitro-3-(trifluoromethylsulfonyloxy)benzyl pivalate (CAS 929095-35-2)
- 2-(Allylthio)-5-(4-bromophenyl)-1-(p-tolyl)-1H-imidazole (CAS 1207044-01-6)
- Trazodone Impurity 3 (CAS CATO-C4X-17723)
- Loxoprofen Impurity 25 (CAS 1091621-63-4)
- Lafutidine Impurity 9 (CAS 1340593-49-8（free base）)
- N-(3-bromobenzyl)isobutyramide (CAS 932942-99-9)
- 1,1,1,4,4,4-Hexafluoro-2-butanone (CAS 400-49-7)
- 2-(2-Methoxyphenyl)-1,1-diphenylethanol (CAS 1251018-59-3)
- 3-[(2E)-3-(4-Chlorophenyl)prop-2-enoyl]-4-hydroxy-6-methyl-2H-pyran-2-one (CAS 14073-08-6)
- (5Z)-4-Chloro-N-(4-chlorophenyl)-5H-1,2,3-dithiazol-5-imine (CAS 174969-54-1)
- 2-Methylquinolizin-5-ium bromide (CAS 5520-34-3)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
Why CATO?
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