Terazosin EP Impurity F CAS 109678-71-9
| CAS No. | 109678-71-9 |
| Molecular Formula | C19H27N5O4 |
| Molecular Weight | 389.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Terazosin EP Impurity F.
As a process- or degradation-related impurity, Terazosin EP Impurity F (CAS 109678-71-9, C19H27N5O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Terazosin EP Impurity F is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 389.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H27N5O4 |
| Molecular Weight | 389.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 5 |
Related Terazosin Standards
- Terazosin EP Impurity J (CAS 152551-75-2)
- Terazosin Impurity 23 (CAS 1260939-66-9)
- Terazosin EP Impurity B (CAS 1177261-73-2)
- (R)-Terazosin (CAS 109351-34-0)
- Terazosin-d8 (CAS 1006718-20-2)
- Terazosin EP Impurity K (CAS 19216-56-9)
- Terazosin EP Impurity I (CAS 1177261-85-6)
- Terazosin EP Impurity H HCl (CAS 111013-28-6)
Recommended Standards
- Nizatidine impurity 16 (CAS CATO-C4X-138016)
- Alfuzosin EP Impurity C (CAS 98902-34-2)
- Posaconazole Impurity 59 (CAS CATO-C4X-120859)
- Upadacitinib Impurity 118 (CAS CATO-C4X-2405118)
- Dapoxetine Impurity 96 (CAS CATO-C4X-143996)
- Ciprofloxacin EP Impurity F (CAS 226903-07-7)
- Aciclovir Impurity 41 (CAS CATO-C4X-101041)
- 5,8-Difluoro-3,4-dihydronaphthalen-1(2H)-one (CAS 501373-03-1)
- Ethyl 4-(pyridin-2-yl)benzoate (CAS 4385-61-9)
- 4-Chloro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1196507-58-0)
- 1-(4-Bromo-2-fluorophenyl)-3-(2,4-dimethylphenyl)propan-1-one (CAS 898794-36-0)
- 3,4-Diethyl-1H-pyrrole-2,5-dione (CAS 34085-07-9)
- tert-Butyl ((1S,4S)-4-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl)carbamate (CAS 1351997-30-2)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
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