Upadacitinib Impurity 118 CAS CATO-C4X-2405118
| CAS No. | CATO-C4X-2405118 |
| Molecular Formula | C22H23N5O2 |
| Molecular Weight | 389.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C22H23N5O2, Upadacitinib Impurity 118 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 389.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Upadacitinib Impurity 118 (CAS CATO-C4X-2405118), a pharmacopoeial impurity reference standard (molecular formula C22H23N5O2, MW 389.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H23N5O2 |
| Molecular Weight | 389.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Upadacitinib Standards
- Upadacitinib Impurity 12 (CAS 2095311-51-4)
- Upadacitinib Impurity 8 (CAS CATO-C4X-24058)
- Upadacitinib Impurity 95 (CAS CATO-C4X-240595)
- (±)-Upadacitinib (CAS 1831899-72-9)
- Upadacitinib Impurity 15 (CAS 1201187-44-1)
- Upadacitinib Impurity 197 (CAS CATO-C4X-2405197)
- Upadacitinib Impurity 133 (CAS CATO-C4X-2405133)
- Upadacitinib Impurity 134 (CAS CATO-C4X-2405134)
Recommended Standards
- Alfuzosin EP Impurity C (CAS 98902-34-2)
- Nizatidine impurity 16 (CAS CATO-C4X-138016)
- Terazosin EP Impurity F (CAS 109678-71-9)
- Terazosin Impurity 23 (CAS 1260939-66-9)
- Ampicillin Impurity 77 (CAS CATO-C4X-144377)
- Roxatidine Impurity 9 (CAS CATO-C4X-12139)
- Phytomenadione/Vitamin K1 Impurity 86 (CAS CATO-C4X-220786)
- 2-methoxycyclohexane-1-sulfonyl chloride (CAS 1247213-60-0)
- 4-Acetamido-6-nitroisophthalic acid (CAS 342045-62-9)
- 4-Propan-2-yl-3H-quinazolin-2-one (CAS 107289-03-2)
- 2-(5-Amino-1,2,4-Thiadiazol-3-yl)-2-(Methoxyimino)Acetic Acid (CAS 72217-12-0)
- (R)-2-amino-4-(3-fluorophenyl)butanoic acid (CAS 1260618-48-1)
- [5-(3-chlorophenyl)-1,3-oxazol-2-yl]methanol (CAS 1155531-69-3)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com