Methylcobalamin Impurity 19 CAS 1098-68-6
| CAS No. | 1098-68-6 |
| Molecular Formula | C14H19N2O7P |
| Molecular Weight | 358.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Methylcobalamin Impurity 19 (CAS 1098-68-6, C14H19N2O7P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Methylcobalamin Impurity 19 (C14H19N2O7P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.5, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 358.28 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Methylcobalamin Impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H19N2O7P |
| Molecular Weight | 358.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Methylcobalamin Standards
Recommended Standards
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- N-(4-bromo-3-methylphenyl)-2-((5-methyl-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 331459-84-8)
- [4-(2,2,2-Trifluoroacetamido)-4H,5H,6H-cyclopenta[b]thiophen-6-ylidene]amino furan-2-carboxylate (CAS 866019-30-9)
- Fasudil Impurity 27 (CAS 5451-44-5)
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- 1047620-49-4 6-Propyl-benzo[1,3]dioxol-5-ylamine hydrochloride 8025AC C10H14ClNO2 (CAS 1047620-49-4)
- 5-Hydroxy-6-(trifluoromethyl)picolinic acid (CAS 1256809-93-4)
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- 1,3-Diethyl 2-(3-methylbut-2-en-1-yl)propanedioate (CAS 22539-80-6)
- (R)-4-(tert-Butyl)oxazolidine-2,5-dione (CAS 1260587-82-3)
- 6-ethynylpyridin-3-amine (CAS 1256824-94-8)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
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