Methyl 2,2-difluoro-2-iodoacetate CAS 109872-87-9
| CAS No. | 109872-87-9 |
| Molecular Formula | C3H3F2IO2 |
| Molecular Weight | 235.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Methyl 2,2-difluoro-2-iodoacetate (CAS 109872-87-9), a certified reference material (molecular formula C3H3F2IO2, MW 235.96 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 2,2-difluoro-2-iodoacetate (C3H3F2IO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H3F2IO2 |
| Molecular Weight | 235.96 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/I-containing |
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Recommended Standards
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- Salbutamol Impurity 87 (CAS 115787-53-6)
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- 2-Thiomorpholinoacetamide (CAS 765242-43-1)
- 7-Bromo-2-(2-fluoropyridin-4-yl)-[1,2,4]triazolo[1,5-a]pyridine (CAS 1380332-02-4)
- ethyl 3-(4-fluorophenyl)-1H-indole-2-carboxylate (CAS 93957-39-2)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
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