Tepotinib Impurity N54 CAS 1103506-79-1
| CAS No. | 1103506-79-1 |
| Molecular Formula | C22H15N5O2 |
| Molecular Weight | 381.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tepotinib Impurity N54 (C22H15N5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Tepotinib Impurity N54 (CAS 1103506-79-1), a pharmacopoeial impurity reference standard (molecular formula C22H15N5O2, MW 381.39 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tepotinib Impurity N54 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H15N5O2 |
| Molecular Weight | 381.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 5 |
Related Tepotinib Standards
- Tepotinib impurity 20 (CAS CATO-C4X-337420)
- Tepotinib impurity 14 (CAS CATO-C4X-337414)
- Tepotinib impurity 23 (CAS CATO-C4X-337423)
- Tepotinib impurity 21 (CAS CATO-C4X-337421)
- Tepotinib impurity 16 (CAS CATO-C4X-337416)
- Tepotinib impurity 27 (CAS CATO-C4X-337427)
- Tepotinib impurity 28 (CAS CATO-C4X-337428)
- Tepotinib impurity 11 (CAS CATO-C4X-337411)
Recommended Standards
- Methyl 3-(4-(3-(3-(trifluoromethyl)phenyl)-1H-pyrazol-5-yl)piperidin-1-yl)propanoate (CAS 1030386-15-2)
- (S)-2-Amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)amino)butanoic acid (CAS 111770-79-7)
- Minoxidil Impurity 16 (CAS CATO-C4X-170016)
- 4-Amino-6-(naphthalen-1-yl)-3-phenyl-3,7-dihydropyrimido[5,4-d]pyrimidine-2,8-dione (CAS 1119392-02-7)
- Atrasentan Impurity 191 (CAS CATO-C4X-3347191)
- Perampanel Impurity 5 (CAS 380918-54-7)
- Solriamfetol Impurity 26 (CAS CATO-C4X-256326)
- 1H-Pyrazol-4-amine, 5-iodo-1-methyl-, hydrochloride (1:2) (CAS 2138174-19-1)
- 3-Ethyl-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 64880-80-4)
- N-(1-(bicyclo[2.2.1]Heptan-2-yl)ethyl)-2-methylpropan-1-amine (CAS 1217642-51-7)
- n-(2-Chloroethyl)aniline (CAS 935-06-8)
- 2,2,2-Trifluoro-1-(4-fluoro-3-(isopentyloxy)phenyl)ethanone (CAS 1443303-09-0)
- Diethyl 2-(dicyclopropylmethyl)malonate (CAS 2755966-09-5)
- Fas C- Terminal Tripeptide (CAS 189109-90-8)
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