(R)-(-)-Camptothecin CAS 110351-92-3
| CAS No. | 110351-92-3 |
| Molecular Formula | C20H16N2O4 |
| Molecular Weight | 348.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-(-)-Camptothecin.
CATO supplies (R)-(-)-Camptothecin (CAS 110351-92-3), a certified reference material (molecular formula C20H16N2O4, MW 348.35 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, (R)-(-)-Camptothecin is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 348.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16N2O4 |
| Molecular Weight | 348.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related R Standards
- (R)-Camptothecin (CAS 1083-11-0)
- (S)-(+)-Camptothecin (CAS 7689-03-4)
- Camptothecin Impurity N3 (CAS 119403-33-7)
- Camptothecin Impurity 16 (CAS 870527-52-9)
- (R)-(-)-Camptothecin-d5 (CAS 1329793-44-3)
- (S)-(+)-Camptothecin D5 (CAS 1329616-37-6)
- 7-Methyl Camptothecin (CAS 78287-26-0)
- Camptothecin Impurity 10 (CAS 68426-53-9)
Recommended Standards
- 2-(3,6-Dihydroxy-9H-xanthen-9-yl)benzohydrazide (CAS 109653-47-6)
- 2-Amino-7,7-dimethyl-1',3',5-trioxo-1',3',5,6,7,8-hexahydrospiro[chromene-4,2'-indene]-3-carbonitrile (CAS 119771-42-5)
- N,N'-(1,2-Phenylene)bis(2-hydroxybenzamide) (CAS 103528-00-3)
- 4'-Methoxyagarotetrol (CAS 123278-01-3)
- 3,3-Bis(azidomethyl)thietane 1,1-dioxide (CAS 1422496-57-8)
- 4-(Benzyloxy)-N-methylaniline (CAS 1142-18-3)
- 2-((4-Chlorophenyl)thio)-N-(4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)acetamide (CAS 701240-34-8)
- Onitisin (CAS 53823-03-3)
- Dansyl Chloride (CAS 605-65-2)
- 2-(Difluoromethyl)naphthalene (CAS 140135-76-8)
- 3-Phenyl-1,2,4-oxadiazole-5-carbonitrile (CAS 37760-53-5)
- 3-Amino-4-chloro-N-(2-hydroxyethyl)-N-methylbenzenesulfonamide (CAS 1098363-97-3)
- 1-Bromo-3-ethynyl-5-methoxybenzene (CAS 2279122-91-5)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com