Sunitinib Impurity 27 CAS 1104253-05-5
| CAS No. | 1104253-05-5 |
| Molecular Formula | C18H17FN2O3 |
| Molecular Weight | 328.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sunitinib Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Sunitinib Impurity 27 (CAS 1104253-05-5) is a certified pharmaceutical impurity reference standard with the molecular formula C18H17FN2O3 and a molecular weight of 328.34 g/mol.
Structurally, Sunitinib Impurity 27 (C18H17FN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 328.34 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H17FN2O3 |
| Molecular Weight | 328.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Sunitinib Standards
- Sunitinib Impurity 24 (CAS 1467015-10-6)
- Sunitinib Impurity 26 (CAS 1348032-93-8)
- Sunitinib Impurity 38 (CAS CATO-C4X-133338)
- Sunitinib Impurity 84 (CAS CATO-C4X-133384)
- Sunitinib Impurity 35 (CAS CATO-C4X-133335)
- Sunitinib Impurity 20 (CAS 873077-70-4)
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Recommended Standards
- Omeprazole Impurity 16 (CAS CATO-C4X-125516)
- Imipenem Impurity 130 (CAS CATO-C4X-1662130)
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- Venetoclax Impurity 72 (CAS 2007920-25-2)
- Linagliptin impurity 154 (CAS 1383917-84-7)
- Avibactam Impurity 53 (CAS CATO-C4X-134853)
- Atorvastatin Impurity 86 (CAS 1046118-44-8)
- Sodium Cholate (CAS 361-09-1)
- Sitafloxacin Impurity 23 (CAS 147782-16-9)
- Androsta-3,5,16-trien-17-ol Trifluoromethanesulfonate (CAS 154229-36-4)
- 2-((1H-Pyrrol-2-yl)methylene)-N-(3-chlorophenyl)hydrazinecarboxamide (CAS 119033-98-6)
- 3-(4-tert-Butylphenoxy)propane-1-sulfonyl chloride (CAS 1018288-96-4)
- (5-(Furan-2-yl)isoxazol-3-yl)methyl benzo[d]thiazole-2-carboxylate (CAS 1207048-59-6)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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