4-Bromo-2,5-difluorophenylboronic Acid CAS 1106676-82-7
| CAS No. | 1106676-82-7 |
| Molecular Formula | C6H4BBrF2O2 |
| Molecular Weight | 236.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Bromo-2,5-difluorophenylboronic Acid (CAS 1106676-82-7), a certified reference material (molecular formula C6H4BBrF2O2, MW 236.81 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, 4-Bromo-2,5-difluorophenylboronic Acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.81 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4BBrF2O2 |
| Molecular Weight | 236.81 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- (2-Bromo-3,6-difluorophenyl)boronic acid (CAS 1260757-41-2)
- 2-Bromo-4,6-difluorophenylboronic Acid (CAS 1315339-48-0)
- (2-Bromo-4,5-difluorophenyl)boronic acid (CAS 849062-34-6)
- (3-Bromo-2,4-difluorophenyl)boronic acid (CAS 2377609-38-4)
- (4-Bromo-2,3-difluorophenyl)boronic acid (CAS 374790-99-5)
- (6-Bromo-2,3-difluorophenyl)boronic acid (CAS 870718-10-8)
- 3-Bromo-2,6-difluorophenylboronic Acid (CAS 352535-84-3)
- 4-Bromo-2,6-difluorophenylboronic Acid (CAS 352535-81-0)
Recommended Standards
- 2,2-Dimethyl-1,3,2-dioxastannolane-4,5-dione (CAS 4166-32-9)
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- 1-Chloro-13-Fluorotridecane (CAS 334-75-8)
- 5-(Tert-butyl)-2-(2-chloroallyl)-1,3-dimethylbenzene (CAS 951893-11-1)
- 4-(4-Heptyl-5-methyl-4H-1,2,4-triazol-3-yl)-1-methyl-1H-pyrazol-5-amine (CAS 956368-27-7)
- (E)-N-(3-bromo-4-methylphenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide (CAS 329778-42-9)
- tert-Butyl 3-((2-amino-N-methylacetamido)methyl)pyrrolidine-1-carboxylate (CAS 1353987-96-8)
- 2-Ethyl-5-nitrobenzoic acid (CAS 90564-19-5)
- [(4-bromo-1-ethyl-1h-pyrazol-3-yl)methyl](methyl)amine (CAS 1001500-18-0)
- Benzyl 3-(1-aminoethyl)morpholine-4-carboxylate (CAS 1934434-12-4)
- 2-Chloro-N-(4-isopropoxyphenyl)acetamide (CAS 100129-54-2)
- 3-(Oxazol-5-yl)benzenesulfonamide (CAS 2167530-18-7)
- 2-Bromo-5-(3-chloropropyl)aniline (CAS 1806433-11-3)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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