4-Bromo-2,6-difluorophenylboronic Acid CAS 352535-81-0
| CAS No. | 352535-81-0 |
| Molecular Formula | C6H4BBrF2O2 |
| Molecular Weight | 236.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Bromo-2,6-difluorophenylboronic Acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Bromo-2,6-difluorophenylboronic Acid (CAS 352535-81-0), molecular formula C6H4BBrF2O2 and molecular weight 236.81 g/mol, is a CATO reference standard with documented purity and traceability.
4-Bromo-2,6-difluorophenylboronic Acid (C6H4BBrF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Bromo-2,6-difluorophenylboronic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4BBrF2O2 |
| Molecular Weight | 236.81 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-Bromo-2,5-difluorophenylboronic Acid (CAS 1106676-82-7)
- (2-Bromo-3,6-difluorophenyl)boronic acid (CAS 1260757-41-2)
- 2-Bromo-4,6-difluorophenylboronic Acid (CAS 1315339-48-0)
- (2-Bromo-4,5-difluorophenyl)boronic acid (CAS 849062-34-6)
- (3-Bromo-2,4-difluorophenyl)boronic acid (CAS 2377609-38-4)
- (4-Bromo-2,3-difluorophenyl)boronic acid (CAS 374790-99-5)
- (6-Bromo-2,3-difluorophenyl)boronic acid (CAS 870718-10-8)
- 3-Bromo-2,6-difluorophenylboronic Acid (CAS 352535-84-3)
Recommended Standards
- 5-Bromo-2,3-difluorophenylboronic acid (CAS 2096339-65-8)
- 5-Bromo-2,4-difluorophenylboronic Acid (CAS 2096331-76-7)
- Tert-butyl((5-chloropentyl)oxy)dimethylsilane (CAS 85514-44-9)
- 4-Chlorobutylzinc bromide (CAS 155589-48-3)
- Ethyl 2-(bromomethyl)nicotinate hydrochloride (CAS 90561-86-7)
- 2,4,7-TRIIODOFLUORESCEIN (CAS 83498-90-2)
- (cis-9)-2-Hydroxy-2-methyl-octadecenoic Acid (CAS 1159977-39-5)
- n-(1-(4-Chlorophenyl)ethyl)propan-1-amine (CAS 209051-17-2)
- Pyrrolo[2,1-b]quinazoline-1-carboxylic acid, 1,2,3,9-tetrahydro-, (1S)- (CAS 481710-98-9)
- 4,4'-Methylenebis(2-Isopropyl-6-Methyllaniline) (CAS 16298-38-7)
- 2-[(3-Phenoxyphenyl)methylene]-1H-indene-1,3(2H)-dione (CAS 400833-57-0)
- (3-Chloroimidazo[1,2-a]pyridin-8-yl)methanol (CAS 167884-27-7)
- N-((1S,2S)-2-((3,5-Di-tert-butyl-2-ethoxyphenyl)selanyl)-2,3-dihydro-1H-inden-1-yl)-1,1,1-trifluoromethanesulfonamide (CAS 2369588-25-8)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
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