(4-Bromo-2,3-difluorophenyl)boronic acid CAS 374790-99-5
| CAS No. | 374790-99-5 |
| Molecular Formula | C6H4BBrF2O2 |
| Molecular Weight | 236.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (4-Bromo-2,3-difluorophenyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (4-Bromo-2,3-difluorophenyl)boronic acid (CAS 374790-99-5), a certified reference material (molecular formula C6H4BBrF2O2, MW 236.81 g/mol) for analytical method development and quality control.
The molecular framework of (4-Bromo-2,3-difluorophenyl)boronic acid (C6H4BBrF2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (4-Bromo-2,3-difluorophenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4BBrF2O2 |
| Molecular Weight | 236.81 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-Bromo-2,5-difluorophenylboronic Acid (CAS 1106676-82-7)
- (2-Bromo-3,6-difluorophenyl)boronic acid (CAS 1260757-41-2)
- 2-Bromo-4,6-difluorophenylboronic Acid (CAS 1315339-48-0)
- (2-Bromo-4,5-difluorophenyl)boronic acid (CAS 849062-34-6)
- (3-Bromo-2,4-difluorophenyl)boronic acid (CAS 2377609-38-4)
- (6-Bromo-2,3-difluorophenyl)boronic acid (CAS 870718-10-8)
- 3-Bromo-2,6-difluorophenylboronic Acid (CAS 352535-84-3)
- 4-Bromo-2,6-difluorophenylboronic Acid (CAS 352535-81-0)
Recommended Standards
- 5-Bromo-2,3-difluorophenylboronic acid (CAS 2096339-65-8)
- (R)-3-(tert-Butyldimethylsilyloxy)-4-chlorobutanal (CAS 119136-98-0)
- 5-Bromo-2,4-difluorophenylboronic Acid (CAS 2096331-76-7)
- Tert-butyl((5-chloropentyl)oxy)dimethylsilane (CAS 85514-44-9)
- 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, polymer with 2-methoxyethyl 2-methyl-2-propenoate (CAS 29403-24-5)
- SAYTEX RB-79 (CAS 77098-07-8)
- β-Methylcholine (CAS 7562-87-0)
- 2',3'-O-(1-Methoxyethylidene)-inosine (CAS 65870-99-7)
- Ethyl 2-(3-amino-1,1-dioxidotetrahydro-2H-thiopyran-3-yl)acetate (CAS 1536787-22-0)
- Rasagiline Impurity 71 (CAS CATO-C4X-191371)
- Tert-butyl (3-hydroxy-1,5-naphthyridin-2-yl)carbamate (CAS 2435612-64-7)
- Propanoic-13C3 Acid (CAS 153474-35-2)
- 3-(1-(Tert-butoxycarbonyl)piperidin-3-yl)isoxazole-5-carboxylic acid (CAS 1361116-93-9)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com