Metoclopramide Impurity 11 CAS 111049-74-2
| CAS No. | 111049-74-2 |
| Molecular Formula | C11H11Cl2NO4 |
| Molecular Weight | 292.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Metoclopramide Impurity 11 (C11H11Cl2NO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Metoclopramide Impurity 11 (CAS 111049-74-2), a pharmacopoeial impurity reference standard (molecular formula C11H11Cl2NO4, MW 292.12 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Metoclopramide Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11Cl2NO4 |
| Molecular Weight | 292.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Metoclopramide Standards
- Metoclopramide impurity 48 (CAS CATO-C4X-141548)
- Metoclopramide EP Impurity F (CAS 38339-95-6)
- Metoclopramide Impurity 68 (CAS 101385-94-8)
- Metoclopramide Impurity 66 (CAS CATO-C4X-141566)
- Metoclopramide Impurity 128 (CAS 880340-01-2)
- Metoclopramide impurity 53 (CAS CATO-C4X-141553)
- Metoclopramide Impurity 20 (CAS 58590-44-6)
- Metoclopramide Impurity 92 (CAS CATO-C4X-141592)
Recommended Standards
- Diclofenac Impurity 45 (CAS 24542-74-3)
- 4-(6-Bromo-pyridin-2-yl)-2-methyl-benzoic acid (CAS 1020718-62-0)
- CAS 21231-80-1 (CAS 21231-80-1)
- 4-(6-Bromopyridin-2-yl)-3-methylbenzoic acid (CAS 1020718-68-6)
- Azelnidipine Impurity 10 (CAS CATO-C4X-104010)
- Urapidil Impurity 40 (CAS 6328-48-9)
- Lodoxamide Impurity 7 (CAS 471-46-5)
- Bis(6-methylpyridin-2-yl)methanone (CAS 99765-49-8)
- n1-(4-Methylthiazol-2-yl)ethane-1,2-diamine (CAS 1016523-93-5)
- Tert-butyl 2-methyl-7,8-dihydropyrido[3,2-d]pyrimidine-5(6H)-carboxylate (CAS 1421312-15-3)
- 2-(3,4-Difluorophenoxy)aniline (CAS 640766-59-2)
- (2-Chloro-4-(1H-pyrazol-1-yl)phenyl)methanol (CAS 1696904-51-4)
- N-[Amino(imino)methyl]-4-benzylpiperazine-1-carboximidamide (CAS 746564-53-4)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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