Lusutrombopag Impurity 18 CAS 1110767-94-6
| CAS No. | 1110767-94-6 |
| Molecular Formula | C15H23BrO2 |
| Molecular Weight | 315.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Lusutrombopag Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Lusutrombopag Impurity 18 (CAS 1110767-94-6) is a certified pharmaceutical impurity reference standard with the molecular formula C15H23BrO2 and a molecular weight of 315.25 g/mol.
Structurally, Lusutrombopag Impurity 18 (C15H23BrO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 315.25 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C15H23BrO2 |
| Molecular Weight | 315.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 11 (CAS CATO-C4X-208411)
- Lusutrombopag Impurity N1 (CAS 1110767-96-8)
- Lusutrombopag Impurity 10 (CAS CATO-C4X-208410)
- Lusutrombopag Impurity 30 (CAS 1110767-19-5)
- Lusutrombopag Impurity 87 (CAS CATO-C4X-208487)
- Lusutrombopag Impurity 68 (CAS CATO-C4X-208468)
- Lusutrombopag Impurity N3 (CAS 1110767-89-9)
- Lusutrombopag Impurity N4 (CAS 1110767-98-0)
Recommended Standards
- tert-Butyl({[4-(2,5-dichlorophenyl)-1,3-thiazol-2-yl]methyl})amine (CAS 1282775-94-3)
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- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)azepane (CAS 1315278-37-5)
- Vilanterol Impurity 65 (CAS 503068-31-3)
- Haloperidol Impurity N1 (CAS 939-52-6)
- Ruilugoli lmpurity 132 (CAS CATO-C4X-2429132)
- Midecamycin Impurity 22 (CAS CATO-C4X-312222)
- N-(3-nitrophenyl)-1,1,1-triphenyl-lambda5-phosphanimine (CAS 14796-86-2)
- 4-Amino-1-(2,6-difluorobenzyl)pyrrolidin-2-one hydrochloride (CAS 1172854-21-5)
- Bis(1,4-di-t-butyl-1,3-diazabutadienyl)cobalt(II) (CAS 177099-51-3)
- 5-Amino-2-(trifluoromethyl)phenol (CAS 106877-47-8)
- 4,8-Dimethyl-2-(4-methylpiperazin-1-yl)quinoline (CAS 338415-75-1)
- Chloroacetic anhydride (CAS 541-88-8)
- D-Phe22-Tirzepatide (CAS CATO-CPTD788912)
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