Ketotifen Impurity 23 CAS 111428-56-9
| CAS No. | 111428-56-9 |
| Molecular Formula | C14H9BrO2S |
| Molecular Weight | 321.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ketotifen Impurity 23 (CAS 111428-56-9) is a certified pharmaceutical impurity reference standard with the molecular formula C14H9BrO2S and a molecular weight of 321.19 g/mol.
Structurally, Ketotifen Impurity 23 (C14H9BrO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 321.19 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ketotifen Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9BrO2S |
| Molecular Weight | 321.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Br-containing |
| Sulfur Atoms | 1 |
Related Ketotifen Standards
- Ketotifen Impurity 15 (CAS CATO-C4X-204615)
- Ketotifen Impurity 28 (CAS CATO-C4X-204628)
- Ketotifen EP Impurity G (CAS 43076-16-0)
- Ketotifen Impurity 30 (CAS CATO-C4X-204630)
- Ketotifen Impurity 34 (CAS CATO-C4X-204634)
- Ketotifen Impurity 35 (CAS CATO-C4X-204635)
- Ketotifen EP Impurity D (CAS 88456-70-6)
- Ketotifen EP Impurity C (CAS 126939-27-3)
Recommended Standards
- 1818AE 2-Bromo-N-{4-[(dimethylamino)sulfonyl]-phenyl}acetamide 37103-21-2 C10H13BrN2O3S (CAS 37103-21-2)
- Ledipasvir Impurity 44 (CAS CATO-C4X-331344)
- tert-Butyl (5-bromo-2-carbamoylthiophen-3-yl)carbamate (CAS 494833-78-2)
- 1-Methanesulfonyl-1H-indole-boronic acid pinacol ester (CAS 1042917-73-6)
- Bilastine impurity 59 (CAS CATO-C4X-225359)
- Faropenem Impurity 15 (CAS 106560-32-1)
- Propranolol Impurity 64 (CAS 68884-32-2)
- Tert-butyl 3-methyl-2,3,4,5-tetrahydro-1h-1,5-benzodiazepine-1-carboxylate (CAS 1375473-73-6)
- (S)-1,4-Di-tert-butyl 2-methyl piperazine-1,2,4-tricarboxylate (CAS 958635-19-3)
- 1,5-Difluoronaphthalene (CAS 315-58-2)
- 2-Amino-N-[3-(methylsulfamoyl)phenyl]propanamide hydrochloride (CAS 1258639-56-3)
- 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2,3-e][1,4]diazepin-6-one (CAS 133627-24-4)
- 4,5-Difluoro-2-nitrobenzamide (CAS 329939-78-8)
- [D-His1]-Semaglutide (CAS CATO-C4X-2226127)
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