Amlodipine Impurity N2 CAS 111429-90-4
| CAS No. | 111429-90-4 |
| Molecular Formula | C15H15NO6 |
| Molecular Weight | 305.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 305.28 g/mol gives Amlodipine Impurity N2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Amlodipine Impurity N2 (CAS 111429-90-4, C15H15NO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Amlodipine Impurity N2 (C15H15NO6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H15NO6 |
| Molecular Weight | 305.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 1 |
Related Amlodipine Standards
- Amlodipine Impurity N13 (CAS 70677-78-0)
- Amlodipine Impurity 114 (CAS CATO-C4X-1095114)
- Amlodipine Impurity 79 (CAS 3516-73-2)
- Amlodipine Impurity 134 (CAS CATO-C4X-1095134)
- Amlodipine Impurity 77 (CAS 265136-65-0)
- Amlodipine Impurity 27 (CAS 88150-75-8)
- Amlodipine Impurity 156 (CAS CATO-C4X-1095156)
- Amlodipine Impurity 48 (CAS CATO-C4X-109548)
Recommended Standards
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