1,5-Difluoronaphthalene CAS 315-58-2
| CAS No. | 315-58-2 |
| Molecular Formula | C10H6F2 |
| Molecular Weight | 164.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1,5-Difluoronaphthalene (CAS 315-58-2) is a high-purity analytical reference standard with the molecular formula C10H6F2 and a molecular weight of 164.15 g/mol.
The molecular framework of 1,5-Difluoronaphthalene (C10H6F2) is characterized by fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6F2 |
| Molecular Weight | 164.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Difluoronaphthalene Standards
- 1,8-Difluoronaphthalene, 97% (CAS 30389-93-6)
- 2,6-Difluoronaphthalene (CAS 59079-69-5)
- 7,8-Difluoronaphthalene-1,3-diol (CAS 2858674-29-8)
- 1-Acetyl-4,5-difluoronaphthalene, 97% (CAS 405196-53-4)
- 4,5-Difluoronaphthalene-1-carboxylic acid, 97% (CAS 405196-37-4)
- 5,7-Difluoronaphthalene-1-carboxylic acid, 97% (CAS 405196-34-1)
- 6,7-Difluoronaphthalene-1-carboxylic acid, 97% (CAS 405196-36-3)
Recommended Standards
- 1-(3-Amino-3-(difluoromethyl)azetidin-1-yl)ethan-1-one (CAS 2875097-13-3)
- 1-(2,2-Difluorocyclopropyl)Ethyl Acetate (CAS 509072-71-3)
- 1-Amino-3,3-difluoro-N-methylcyclobutane-1-carboxamide (CAS 2193057-38-2)
- (S)-3,3-difluorocyclohexane-1-carboxylic acid (CAS 2199500-65-5)
- 1-Chloro-2-ethyl-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile (CAS 305334-58-1)
- 4-Methyl-N-(2-(2-methylbenzoyl)-3-oxo-2,3-dihydro-1,2,4-thiadiazol-5-yl)benzamide (CAS 478031-95-7)
- 5-[4-(1H-Imidazol-1-yl)phenyl]-1,2-oxazole (CAS 314268-36-5)
- N-[3-(3-oxobutanoyl)phenyl]acetamide (CAS 88636-74-2)
- Methyl 3-(1-benzyl-4-pyrrolidin-1-ylpiperidin-3-yl)propanoate oxalate (CAS 1332530-18-3)
- 3-(4,4-Difluorocyclohexyl)-3-oxopropanenitrile (CAS 1546403-48-8)
- (3-(1H-Indol-6-yl)phenyl)methanol (CAS 1349717-81-2)
- (R)-5-(1-Methylpyrrolidin-2-yl)pyridin-2(1H)-one (CAS 22956-40-7)
- 1-(2,4-Dichloro-6-hydroxy-3-methoxyphenyl)naphthalen-2-ol (CAS 1980086-78-9)
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