2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile CAS 1118460-77-7
| CAS No. | 1118460-77-7 |
| Molecular Formula | C27H22N2O3 |
| Molecular Weight | 422.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 1118460-77-7), a certified reference material (molecular formula C27H22N2O3, MW 422.48 g/mol) for analytical method development and quality control.
The molecular framework of 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (C27H22N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H22N2O3 |
| Molecular Weight | 422.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Amino Standards
- Ethyl 4-{5-amino-7-thia-1,9-diazatetracyclo[9.2.2.0^{2,10}.0^{4,8}]pentadeca-2(10),3,5,8-tetraene-6-amido}benzoate (CAS 728003-27-8)
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Recommended Standards
- Methyl 3-(2-(2-(4-acetamidophenoxy)acetyl)hydrazine-1-carbothioamido)thiophene-2-carboxylate (CAS 1022891-22-0)
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- Kuwanon C (CAS 62949-79-5)
- 2,5-Dioxopyrrolidin-1-yl 4-((2-(1,3-dioxoisoindolin-2-yl)ethyl)disulfanyl)butanoate (CAS 1190203-91-8)
- 5-Bromo-6-methoxypyrazin-2-amine (CAS 1245649-92-6)
- Methyl 2-3-di-O-benzoyl-4-6-O-benzylidene-α-D-glucopyranoside (CAS 6748-91-0)
- 1-Cyclohexyl-3,3-dimethylbutan-2-one (CAS 23137-42-0)
- 5-(4-Chlorophenyl)-4-propyl-4h-1,2,4-triazol-3-yl hydrosulfide (CAS 91090-20-9)
- 4-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)morpholine (CAS 957198-29-7)
- 2-Amino-2-cycloheptylethan-1-ol (CAS 1448418-48-1)
- 9-Benzyl-1-oxa-3,9-diazaspiro[5.5]undecan-2-one (CAS 54981-06-5)
- Salcaprozate Impurity 12 (CAS 287935-37-9)
- 2-Chloro-4-fluoro-3-methylaniline (CAS 90292-63-0)
- Semaglutide impurity 29 (CAS 1188328-22-4)
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