4-Amino-2-[(4-chlorophenyl)amino]-5-(2,4-dichlorobenzoyl)thiophene-3-carbonitrile CAS 338966-43-1
| CAS No. | 338966-43-1 |
| Molecular Formula | C18H10Cl3N3OS |
| Molecular Weight | 422.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Amino-2-[(4-chlorophenyl)amino]-5-(2,4-dichlorobenzoyl)thiophene-3-carbonitrile is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Amino-2-[(4-chlorophenyl)amino]-5-(2,4-dichlorobenzoyl)thiophene-3-carbonitrile (CAS 338966-43-1), molecular formula C18H10Cl3N3OS and molecular weight 422.72 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Amino-2-[(4-chlorophenyl)amino]-5-(2,4-dichlorobenzoyl)thiophene-3-carbonitrile (C18H10Cl3N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Amino-2-[(4-chlorophenyl)amino]-5-(2,4-dichlorobenzoyl)thiophene-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10Cl3N3OS |
| Molecular Weight | 422.72 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 4-(2,4-Diphenylpyrimidine-5-carbonyl)morpholine (CAS 338771-93-0)
- Ethyl 6-bromo-2-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (CAS 1704065-81-5)
- 3-(2-Chloropropyl)quinazolin-4(3H)-one (CAS 5270-99-5)
- 2-(Methylthio)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1073354-78-5)
- (4-Bromophenyl)(oxo)acetaldehyde hydrazone (CAS 23722-26-1)
- 5-((4,5-Dihydro-1H-imidazol-2-yl)amino)benzene-1,2,3-triol (CAS 91147-42-1)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
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