Norfloxacin lmpurity 28 CAS 1119454-98-6
| CAS No. | 1119454-98-6 |
| Molecular Formula | C7H2Cl3FO |
| Molecular Weight | 227.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Norfloxacin lmpurity 28 (CAS 1119454-98-6), a pharmacopoeial impurity reference standard (molecular formula C7H2Cl3FO, MW 227.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Norfloxacin lmpurity 28 (C7H2Cl3FO) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Norfloxacin lmpurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H2Cl3FO |
| Molecular Weight | 227.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
Related Norfloxacin Standards
- Norfloxacin lmpurity 29 (CAS 1529604-41-8)
- Norfloxacin Impurity 44 (CAS 140700-98-7)
- Norfloxacin Impurity 38 (CAS CATO-C4X-146838)
- Norfloxacin Impurity 12 (CAS 75001-63-7)
- Norfloxacin Impurity 3 (CAS 16600-24-1)
- Norfloxacin Impurity 32 (CAS 70032-16-5)
- Norfloxacin Impurity 57 (CAS CATO-C4X-146857)
- Norfloxacin Impurity 52 (CAS 7251-32-3)
Recommended Standards
- 916420-63-8 3,6-Dichloro-2-fluorobenzoyl chloride MFCD09025383 (CAS 916420-63-8)
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- CAS 478784-66-6 (CAS 478784-66-6)
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- Z-Phe-Leu-OH (CAS 4313-73-9)
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Why CATO?
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