Norfloxacin lmpurity 29 CAS 1529604-41-8
| CAS No. | 1529604-41-8 |
| Molecular Formula | C7H2Cl3FO |
| Molecular Weight | 227.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Norfloxacin lmpurity 29.
As a process- or degradation-related impurity, Norfloxacin lmpurity 29 (CAS 1529604-41-8, C7H2Cl3FO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Norfloxacin lmpurity 29 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H2Cl3FO |
| Molecular Weight | 227.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Norfloxacin Standards
- Norfloxacin lmpurity 28 (CAS 1119454-98-6)
- Norfloxacin Impurity 44 (CAS 140700-98-7)
- Norfloxacin Impurity 38 (CAS CATO-C4X-146838)
- Norfloxacin Impurity 12 (CAS 75001-63-7)
- Norfloxacin Impurity 3 (CAS 16600-24-1)
- Norfloxacin Impurity 32 (CAS 70032-16-5)
- Norfloxacin Impurity 57 (CAS CATO-C4X-146857)
- Norfloxacin Impurity 52 (CAS 7251-32-3)
Recommended Standards
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- Cefoxitin Impurity 47 (CAS CATO-C4X-157847)
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