Ethyl 1-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate CAS 112055-36-4
| CAS No. | 112055-36-4 |
| Molecular Formula | C13H10ClF3N2O2 |
| Molecular Weight | 318.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 1-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate.
CATO supplies Ethyl 1-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 112055-36-4), a certified reference material (molecular formula C13H10ClF3N2O2, MW 318.68 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 1-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (C13H10ClF3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 1-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10ClF3N2O2 |
| Molecular Weight | 318.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- Ethyl 1-(2-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 1020237-74-4)
- Ethyl 1-(3-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 112055-35-3)
- Ethyl 4-(4-chlorophenyl)-2-(trifluoromethyl)-1h-imidazole-5-carboxylate (CAS 162700-26-7)
- Ethyl 5-(4-chlorophenyl)-2-(trifluoromethyl)furan-3-carboxylate (CAS 175276-59-2)
- 3-(4-Chlorophenyl)-1-(2,4-difluorophenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-76-3)
- N-[5-(3-Chlorophenyl)-2,7-dioxo-1,2,4,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl]acetamide (CAS 1257440-43-9)
- N-(2-Chlorophenyl)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxamide (CAS 297146-24-8)
- 1-[(3-Chlorophenyl)methyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole (CAS 1415825-07-8)
Recommended Standards
- 2-(2-Chloro-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid ethyl ester (CAS 1033586-26-3)
- 1-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-methyl-1H-imidazol-4-yl}-1-ethanone oxime (CAS 251096-48-7)
- 3-Chloro-5-nitro-2-(4-nitrophenyl)-2H-indazole (CAS 88279-21-4)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(furan-2-ylmethyl)acetamide (CAS 691870-10-7)
- 2-(2-Methoxy-3,5-dimethylphenyl)-4-methylpyrrolidine (CAS 603068-97-9)
- (R)-2-(3-fluoro-2-(trifluoromethyl)phenyl)-2-(methylamino)ethan-1-ol (CAS 1335480-05-1)
- 3-bromo-N-[(2,4-dimethoxyphenyl)methyl]propanamide (CAS 1864057-40-8)
- 4-Bromo-N-cyclobutyl-3-methylaniline (CAS 1247401-52-0)
- Ethyl 6-(aminomethyl)nicotinate (CAS 214824-13-2)
- all-trans-Retinal (CAS 116-31-4)
- 5,6-Diamino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one sulfate (CAS 117043-67-1)
- 5-Methyl-4-nitro-1H-indole-2-carbaldehyde (CAS 61149-55-1)
- 1-(3-Fluoro-4-methylphenyl)-1H-pyrrole (CAS 142044-86-8)
- Lixisenatide (CAS 320367-13-3)
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