Ethyl 5-(4-chlorophenyl)-2-(trifluoromethyl)furan-3-carboxylate CAS 175276-59-2
| CAS No. | 175276-59-2 |
| Molecular Formula | C14H10ClF3O3 |
| Molecular Weight | 318.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ethyl 5-(4-chlorophenyl)-2-(trifluoromethyl)furan-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ethyl 5-(4-chlorophenyl)-2-(trifluoromethyl)furan-3-carboxylate (CAS 175276-59-2), molecular formula C14H10ClF3O3 and molecular weight 318.68 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 5-(4-chlorophenyl)-2-(trifluoromethyl)furan-3-carboxylate (C14H10ClF3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H10ClF3O3 |
| Molecular Weight | 318.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl-containing |
Related Ethyl Standards
- Ethyl 1-(2-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 1020237-74-4)
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- Ethyl 1-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 112055-36-4)
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- 3-(4-Chlorophenyl)-1-(2,4-difluorophenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-76-3)
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Recommended Standards
- 1-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-methyl-1H-imidazol-4-yl}-1-ethanone oxime (CAS 251096-48-7)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(furan-2-ylmethyl)acetamide (CAS 691870-10-7)
- 5-Chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one (CAS 2381044-50-2)
- 2-(2-Chloro-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid ethyl ester (CAS 1033586-26-3)
- 1-[(4-Bromo-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)methyl]-4-(4-methoxyphenyl)-1H-1,2,3-triazole-5-carbonitrile (CAS 1024251-40-8)
- [2-(difluoromethoxy)-5-methoxyphenyl]methanol (CAS 294860-72-3)
- 4-Chloro-3-(hydroxymethyl)benzoic acid (CAS 1187238-15-8)
- Methyl 4-Oxotetrahydrothiopyran-3-carboxylate (CAS 4160-61-6)
- 5-(4-Isopropylphenyl)-4-methyl-4H-1,2,4-triazole-3-thiol 669729-28-6 7829AE C12H15N3S (CAS 669729-28-6)
- Methyl 4,6-dimethyl-2-(methylthio)pyrimidine-5-carboxylate (CAS 946488-38-6)
- 1,3-Diphenylurea-d10 (CAS 108009-46-7)
- 3-chloro-2,6-naphthyridine (CAS 52463-33-9)
- 3-Oxo-4-aza-5-androstene-17β-carboxylic acid (CAS 103335-54-2)
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