Ethyl 4-(trifluoromethyl)-1,3-oxazole-5-carboxylate CAS 1126633-32-6
| CAS No. | 1126633-32-6 |
| Molecular Formula | C7H6F3NO3 |
| Molecular Weight | 209.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Ethyl 4-(trifluoromethyl)-1,3-oxazole-5-carboxylate (CAS 1126633-32-6), molecular formula C7H6F3NO3 and molecular weight 209.12 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Ethyl 4-(trifluoromethyl)-1,3-oxazole-5-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 209.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H6F3NO3 |
| Molecular Weight | 209.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 2-(trifluoromethyl)-1,3-oxazole-4-carboxylate (CAS 1060815-99-7)
- Ethyl 5-(trifluoromethyl)oxazole-4-carboxylate (CAS 122019-71-0)
- Ethyl 5-(trifluoromethyl)isoxazole-4-carboxylate (CAS 1341552-49-5)
- 3-(3-(Trifluoromethyl)isoxazol-5-yl)propanoic acid (CAS 1368878-78-7)
- Methyl (2-(trifluoromethyl)furan-3-yl)carbamate (CAS 1378254-88-6)
- Ethyl 4-(Trifluoromethyl)oxazole-2-carboxylate (CAS 2113247-44-0)
- Ethyl 5-(trifluoromethyl)isoxazole-3-carboxylate (CAS 625120-13-0)
- 1-Ethyl-5-(trifluoromethyl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1267110-06-4)
Recommended Standards
- 1-Bromo-4-isobutoxybutane (CAS 1094698-14-2)
- 4,6-dichloro-1-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 114244-83-6)
- 7-Bromo-2-methylheptan-2-ol (CAS 107768-04-7)
- 2,4-Dihydroxy-3-methoxy-6-(trifluoromethyl)pyridine (CAS 1214361-97-3)
- 2-[(E)-[2-[(e)-(2,5-dihydroxyphenyl)methyleneamino]phenyl]iminomethyl]benzene-1,4-diol (CAS 154198-33-1)
- 2-Chloro-1-(1H-indol-1-yl)ethan-1-one (CAS 61995-53-7)
- 2-Bromo-N-(2-butoxyethyl)aniline (CAS 1247450-26-5)
- 1-(2-Aminophenyl)-N,N-dimethylpyrrolidine-2-carboxamide (CAS 1189557-46-7)
- Tert-butyl 1-(hydroxymethyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate hydrochloride (CAS 2448475-38-3)
- 4,4,5,5-Tetramethyl-2-(3,5-dimethyl-4-propan-2-yloxy-phenyl)-1,3,2-dioxaborolane (CAS 2121514-76-7)
- 4,5-Dihydroblumenol A (CAS 155418-97-6)
- n-Isopropyl-1-(2-methoxyethyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide (CAS 1099869-66-5)
- 2-(1,3-Dioxan-2-yl)-5-(trifluoromethyl)thiazole (CAS 2007909-08-0)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
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