Sunitinib-d10 CAS 1126721-82-1
| CAS No. | 1126721-82-1 |
| Molecular Formula | - |
| Molecular Weight | 408.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sunitinib-d10.
CATO supplies Sunitinib-d10 (CAS 1126721-82-1), a certified reference material (molecular formula C22H17D10FN4O2, MW 408.54 g/mol) for analytical method development and quality control.
The molecular framework of Sunitinib-d10 (C22H17D10FN4O2) is characterized by deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H17D10FN4O2 |
| Molecular Weight | 408.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Sunitinib Standards
- Sunitinib Impurity N1 (CAS 2377533-92-9)
- Sunitinib Impurity 81 (CAS CATO-C4X-133381)
- Sunitinib Impurity 65 (CAS CATO-C4X-133365)
- Sunitinib Impurity 2 (CAS 356068-99-0)
- Sunitinib Impurity 74 (CAS CATO-C4X-133374)
- Sunitinib-d4 (CAS 1126721-79-6)
- Sunitinib impurity 69 (CAS CATO-C4X-133369)
- Sunitinib Impurity 28 (CAS CATO-C4X-133328)
Recommended Standards
- Netupitant Impurity 62 (CAS CATO-C4X-122362)
- (R)-1-(3-((Tert-butoxycarbonyl)amino)-4-(phenylthio)butyl)piperidine-4-carboxylic acid (CAS 2447684-22-0)
- Ranolazine Impurity 1 (CAS 380204-72-8)
- Ecabet Impurity 2 (CAS CATO-C4X-16262)
- (4-(Allyloxy)-3-methoxyphenyl)methanamine (CAS 952946-76-8)
- 4-Hydroxy-3-methylisoquinolin-1(2H)-one (CAS 5423-95-0)
- 2-Chloro-7-methoxyquinazolin-4-amine (CAS 1107694-98-3)
- 2-Oxotetrahydrofuran-3-yl 2-(methylthio)nicotinate (CAS 452299-55-7)
- 5-(1-(4-Fluorophenoxy)ethyl)-1,3,4-oxadiazole-2-thiol (CAS 781632-83-5)
- 4-(chloromethyl)pyridine (CAS 10445-91-7)
- Tert-butyl (2-amino-2-(tetrahydro-2H-pyran-4-yl)ethyl)carbamate (CAS 1889688-16-7)
- (4-Fluorophenyl)hydrazine (CAS 371-14-2)
- 1-MEthyl-2-nitro-1h-indole (CAS 271789-32-3)
- Myosin Kinase Inhibiting Peptide (CAS 119386-39-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com