Sunitinib Impurity 2 CAS 356068-99-0
| CAS No. | 356068-99-0 |
| Molecular Formula | C22H27FN4O3 |
| Molecular Weight | 414.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Sunitinib Impurity 2 (CAS 356068-99-0, C22H27FN4O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Sunitinib Impurity 2 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 414.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sunitinib Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27FN4O3 |
| Molecular Weight | 414.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Sunitinib Standards
- Sunitinib Impurity 74 (CAS CATO-C4X-133374)
- Sunitinib Impurity 81 (CAS CATO-C4X-133381)
- Sunitinib Impurity N1 (CAS 2377533-92-9)
- Sunitinib-d10 (CAS 1126721-82-1)
- Sunitinib Impurity 64 (CAS CATO-C4X-133364)
- Sunitinib Impurity 59 (CAS CATO-C4X-133359)
- Sunitinib Impurity 65 (CAS CATO-C4X-133365)
- Sunitinib-d4 (CAS 1126721-79-6)
Recommended Standards
- Ethyl 2-oxo-6-((phenylsulfonyl)methyl)-4-(p-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 902277-65-0)
- 4-(5-(Cyclopentylthio)-4-methyl-4H-1,2,4-triazol-3-yl)-2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazole (CAS 956754-00-0)
- Bis(2-butoxyethyl) 2-(3-Hydroxybutoxy)ethyl Phosphate Triester (CAS 1477494-87-3)
- 2,3:4,5-Di-O-isopropylidene-1-O-p-toluenesulfonyl-β-D-fructopyranose (CAS 78574-35-3)
- Efavirenz Impurity 27 (CAS CATO-C4X-162727)
- Ampicillin Trihydrate EP Impurity M (CAS CATO-C4X-144344)
- Thiamine /Vitamin B1 Impurity 54 Ammonium Salt (CAS 10553-88-5 (free form))
- 6-Chloro-n4-cyclohexylpyrimidine-4,5-diamine (CAS 5449-10-5)
- 2-Chloro-4-hydroxyquinoline-3-carbonitrile (CAS 69875-52-1)
- 2-(4-Methoxyphenylcarbonothioylthio)ethanoic acid (CAS 38204-31-8)
- 7-Iodoisoindolin-1-one (CAS 866766-96-3)
- Methyl 3-formyl-5-methyl-1H-pyrrole-2-carboxylate (CAS 203207-46-9)
- Glutaric Acid (CAS 110-94-1)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com