Olmesartan Impurity 60 CAS 1127249-17-5
| CAS No. | 1127249-17-5 |
| Molecular Formula | C14H10Br2N4 |
| Molecular Weight | 394.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Olmesartan Impurity 60 (CAS 1127249-17-5, C14H10Br2N4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Olmesartan Impurity 60 (C14H10Br2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Olmesartan Impurity 60 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10Br2N4 |
| Molecular Weight | 394.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Olmesartan Standards
- Olmesartan impurity 103 (CAS CATO-C4X-1097103)
- Olmesartan Medoxomil EP Impurity B (CAS 849206-43-5)
- Olmesartan Impurity 21 (CAS 172875-98-8)
- Olmesartan Impurity 92 (CAS CATO-C4X-109792)
- Olmesartan impurity 89 (CAS CATO-C4X-109789)
- Olmesartan Methyl Ketone (CAS 1227626-45-0)
- Olmesartan Medoxomilum EP Impurity A (CAS 144689-24-7)
- Olmesartan- D4 (CAS 1420880-41-6)
Recommended Standards
- tert-Butyl 6,8-dibromo-2H-pyrido[3,2-b][1,4]oxazine-4(3H)-carboxylate (CAS 2758502-26-8)
- Ethyl 4-bromo-7-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylate (CAS 2377609-01-1)
- 6-Bromo-3-(4-bromobenzyl)quinazolin-4(3H)-one (CAS 302913-23-1)
- Dequalinium Impurity 4 (CAS 16355-92-3)
- Butylphthalide Impurity 26 (CAS 20871-40-3)
- Tegoprazan Impurity 137 (CAS CATO-C4X-2297137)
- Dexmedetomidine Impurity 96 (CAS CATO-C4X-123096)
- Zirconia(IV) (CAS 1314-23-4)
- 4-Chloro-2-pyridinecarboxaldehyde (CAS 63071-13-6)
- 1-[(2-chlorophenyl)methyl]-3-phenyl-1h-pyrazole-4-carboxylic acid (CAS 956199-29-4)
- 898838-07-8 2,2,6,6-Tetramethylpiperidinylmagnesium chloride, lithium chloride complex 1.0M (18wt% +/-2wt%) in toluene/THF MFCD12546030 (CAS 898838-07-8)
- Dapagliflozin Impurity 129 (CAS CATO-C4X-1138129)
- (2S,4r,5R)-5-aminospiro[3.3]Heptane-2-carboxylic acid hydrochloride (CAS 1682647-12-6)
- Semaglutide impurity 72 (CAS CATO-C4X-222672)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com