Mesalazine EP Impurity J CAS 112725-89-0
| CAS No. | 112725-89-0 |
| Molecular Formula | C7H8N2O3 |
| Molecular Weight | 168.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Mesalazine EP Impurity J is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Mesalazine EP Impurity J (CAS 112725-89-0, C7H8N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Mesalazine EP Impurity J (C7H8N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Mesalazine EP Impurity J meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O3 |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Mesalazine Standards
Recommended Standards
- Salbutamol Impurity 154 (CAS 82885-62-9)
- Benserazide Impurity 59 (CAS CATO-C4X-142759)
- Lansoprazole Impurity 9 (CAS 37699-43-7)
- Norepinephrine Impurity 54 (CAS CATO-C4X-151454)
- Ritonavir Impurity 61 (CAS CATO-C4X-175161)
- Atorvastatin Impurity 107 (CAS 125995-17-7)
- Tadalafil Impurity 69 (CAS CATO-C4X-108769)
- 5-(2-Bromo-4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole (CAS 2236573-61-6)
- 1-chloro-4-{[(chloromethyl)sulfanyl]methyl}benzene (CAS 15894-25-4)
- Dabigatran Impurity 59 (CAS CATO-C4X-108959)
- 3-Bromo-2-hydroxy-5-methylpyridine (CAS 17282-02-9)
- 7-Methyl-5-phenyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one (CAS 17972-75-7)
- 3-Chloropyridine-2,4-diamine (CAS 1232431-15-0)
- D-Trp25-Tirzepatide (CAS CATO-CPTD788909)
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