Mesalazine Impurity 25 CAS 42753-75-3
| CAS No. | 42753-75-3 |
| Molecular Formula | C8H9NO3 |
| Molecular Weight | 167.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Mesalazine Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Mesalazine Impurity 25 (CAS 42753-75-3) is a certified pharmaceutical impurity reference standard with the molecular formula C8H9NO3 and a molecular weight of 167.16 g/mol.
The molecular framework of Mesalazine Impurity 25 (C8H9NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H9NO3 |
| Molecular Weight | 167.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 1 |
Related Mesalazine Standards
- Mesalazine EP Impurity J (CAS 112725-89-0)
- Mesalazine Impurity 10 (CAS 3958-79-0)
- Mesalazine Impurity 1 (CAS 939-97-9)
- Mesalazine EP Impurity L (CAS 118-91-2)
- Mesalazine-d3 (CAS 1309283-32-6)
- Mesalazine Impurity 3 (CAS 98-73-7)
- Mesalazine EP Impurity G (CAS 490-79-9)
- Mesalazine Impurity 42 (CAS 104786-99-4)
Recommended Standards
- Cefadroxil EP Impurity A(Amoxicillin EP Impurity I) (CAS 22818-40-2)
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- Norepinephrine Impurity 127 (CAS 94593-04-1)
- Laurotetanine impurity 1 (CAS 128-76-7)
- Brivaracetam Impurity 150 (CAS CATO-C4X-2007150)
- Ceftriaxone Sodium EP Impurity B(Cefotaxime EP Impurity E)（Cefodizime Impurity D） (CAS 66340-33-8)
- 1-[1,4]Bipiperidinyl-1-yl-2-chloro-ethanonehydrochloride (CAS 1185299-34-6)
- tert-Butyl 3-((6-bromopyridin-2-yl)(methyl)amino)piperidine-1-carboxylate (CAS 1261232-09-0)
- STACHYOSE (CAS 470-55-3)
- L-Leucine hydrochloride (CAS 760-84-9)
- Manganese(III) oxide (CAS 1317-34-6)
- 2,4,6-Trifluorophenacyl bromide (CAS 746630-36-4)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
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