Propranolol Chloro Impurity CAS 112805-69-3
| CAS No. | 112805-69-3 |
| Molecular Formula | C13H13ClO2 |
| Molecular Weight | 236.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Propranolol Chloro Impurity (CAS 112805-69-3), molecular formula C13H13ClO2 and molecular weight 236.69 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Propranolol Chloro Impurity is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H13ClO2 |
| Molecular Weight | 236.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
Related Propranolol Standards
- Propranolol Impurity 5 (CAS 132005-35-7)
- Propranolol Impurity 24 (CAS 20133-94-2)
- Propranolol Impurity 51 (CAS CATO-C4X-151951)
- Propranolol Impurity 57 (CAS CATO-C4X-151957)
- Propranolol Impurity 6 (CAS 20133-93-1)
- Propranolol impurity 44 (CAS CATO-C4X-151944)
- Propranolol impurity 45 (CAS CATO-C4X-151945)
- Propranolol impurity 46 (CAS CATO-C4X-151946)
Recommended Standards
- (2-Chlorophenyl)-2-propynoic acid tert-butyl ester (CAS 1072190-54-5)
- 1-(4-Fluorophenyl)propane-1-sulfonyl chloride (CAS 1248594-54-8)
- 1-(5-Chlorobenzofuran-2-yl)-2,2-dimethylpropan-1-one (CAS 1040075-54-4)
- Methyl 3-(3-chlorophenyl)bicyclo[1.1.1]Pentane-1-carboxylate (CAS 131515-50-9)
- 5-(Pyridin-3-yl)oxazole-4-carboxylic acid (CAS 1083224-10-5)
- 5-Nitropyridine-2-carboxamidine (CAS 1179533-27-7)
- (R)-3,3'-Bis(3,5-di-tert-butylphenyl)-[1,1'-binaphthalene]-2,2'-diol (CAS 756491-53-9)
- 1-(2-Fluorophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid (CAS 956930-31-7)
- Itopride Impurity 21 (CAS 199679-32-8)
- 2-((Furan-2-ylmethyl)amino)-2-oxoethyl adamantane-1-carboxylate (CAS 380487-05-8)
- (E)-2-(4-chlorobenzylidene)-3,4-dihydronaphthalen-1(2H)-one (CAS 59082-24-5)
- 5-Hydroxy-4-methoxy-N-methylpicolinamide (CAS 871836-34-9)
- 5-Chloro-3-(3,4-dichlorophenyl)benzoic acid (CAS 1261984-79-5)
- C-Peptide（dog） (CAS 39016-05-2)
Why CATO?
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