Rotigotine EP Impurity A CAS 112835-48-0
| CAS No. | 112835-48-0 |
| Molecular Formula | C19H25NOS |
| Molecular Weight | 315.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rotigotine EP Impurity A (C19H25NOS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Rotigotine EP Impurity A (CAS 112835-48-0), a pharmacopoeial impurity reference standard (molecular formula C19H25NOS, MW 315.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H25NOS |
| Molecular Weight | 315.47 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Rotigotine Standards
- Rotigotine (CAS 92206-54-7)
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- Rotigotine Impurity 40 (CAS 102121-00-6)
- Rotigotine USP RC C-D6 N-nitroso (CAS CATO-C4X-192727)
- Rotigotine impurity 19 (CAS CATO-C4X-192719)
- Rotigotine Impurity 26 (CAS CATO-C4X-192726)
- Rotigotine Impurity 34 (CAS CATO-C4X-192734)
- Rotigotine EP Impurity E (CAS 2708278-87-7)
Recommended Standards
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Why CATO?
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