Rotigotine CAS 99755-59-6
| CAS No. | 99755-59-6 |
| Molecular Formula | C19H25NOS |
| Molecular Weight | 315.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rotigotine is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Rotigotine (CAS 99755-59-6), molecular formula C19H25NOS and molecular weight 315.47 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Rotigotine (C19H25NOS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Rotigotine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H25NOS |
| Molecular Weight | 315.47 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Rotigotine Standards
- Rotigotine (CAS 92206-54-7)
- Rotigotine Impurity 40 (CAS 102121-00-6)
- Rotigotine EP Impurity A (CAS 112835-48-0)
- Rotigotine USP RC C-D6 N-nitroso (CAS CATO-C4X-192727)
- Rotigotine impurity 19 (CAS CATO-C4X-192719)
- Rotigotine Impurity 26 (CAS CATO-C4X-192726)
- Rotigotine Impurity 34 (CAS CATO-C4X-192734)
- Rotigotine EP Impurity E (CAS 2708278-87-7)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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