Calcipotriol Impurity 11 CAS 112849-17-9
| CAS No. | 112849-17-9 |
| Molecular Formula | C39H66O3Si2 |
| Molecular Weight | 639.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Calcipotriol Impurity 11 (CAS 112849-17-9, C39H66O3Si2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Calcipotriol Impurity 11 (C39H66O3Si2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 639.11 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Calcipotriol Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C39H66O3Si2 |
| Molecular Weight | 639.11 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
Related Calcipotriol Standards
- Calcipotriol Impurity 29 (CAS CATO-C4X-122229)
- Calcipotriol Impurity 30 (CAS 115648-68-5)
- Calcipotriol Impurity 31 (CAS 866406-02-2)
- Calcipotriol Impurity 23 (CAS 1630745-25-3)
- Calcipotriol Impurity 51 (CAS 910133-69-6)
- Calcipotriol Impurity 10 (CAS 112849-27-1)
- Calcipotriol EP Impurity F (CAS 112875-61-3)
- Calcipotriol Impurity 17 (CAS 115540-28-8)
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