Calcipotriol Impurity 33 CAS 112849-18-0
| CAS No. | 112849-18-0 |
| Molecular Formula | C33H52O2Si |
| Molecular Weight | 508.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Calcipotriol Impurity 33 (CAS 112849-18-0), a pharmacopoeial impurity reference standard (molecular formula C33H52O2Si, MW 508.85 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C33H52O2Si, Calcipotriol Impurity 33 contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 508.85 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C33H52O2Si |
| Molecular Weight | 508.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
Related Calcipotriol Standards
- Calcipotriol Impurity 15 (CAS 104846-63-1)
- Calcipotriol Impurity 38 (CAS CATO-C4X-122238)
- Calcipotriol Impurity 32 (CAS 87407-51-0)
- Calcipotriol Impurity 24 (CAS 112828-13-4)
- Calcipotriol Impurity 28 (CAS CATO-C4X-122228)
- Calcipotriol-D4 (CAS 112965-21-6 (non-labelled))
- Calcipotriol Impurity 21 (CAS 143032-85-3)
- Calcipotriol Impurity 35 (CAS CATO-C4X-122235)
Recommended Standards
- 2,4,6-Trichloro-N-(5,6-dimethyl-1-(3-methylbenzyl)-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 865660-72-6)
- 7-(Chlorodifluoromethyl)-2-(4-phenylpiperazin-1-yl)-5-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 439096-13-6)
- 2,4,6-Trichloro-N-(5,6-dimethyl-1-(2-methylbenzyl)-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338954-82-8)
- N-{2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]-5-(trifluoromethyl)phenyl}thiophene-2-carboxamide (CAS 478262-30-5)
- N-Nitroso Diethyl Ester Methotrexate EP Impurity L (CAS CATO-C4X-115458)
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- Carbocisteine Impurity 30 (CAS CATO-C4X-201030)
- 8-Bromo-5’-O-(4-cyanobenzyl)-2’,3’-di-O-isopropylidene adenosine (CAS 1134156-53-8)
- 4-(Cyclopropylsulfonyl)benzoic acid (CAS 1346608-85-2)
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- 2-((3-Ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 256955-22-3)
- 2-(Cyclohexylthio)-5-nitrobenzoic acid (CAS 773870-54-5)
- 107444-51-9 0JS9125PIZ Glucagon-like peptide 1 (7-36) Glucagon-related peptide 1 (Rana catesbeiana), 3-L-glutamic acid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-30-L-argininamide-31-de-L-proline-32-de-L-lysine- Glp-I (7-36) Proglucagon (78-107) Human glucagon-like peptide-1-(7-36) amide Human GLP-1-(7-36)-amide Glucagon-like peptide-I(7-36) amide Rat GLP-I(7-36)amide Insulinotropin (human) MKC 253 UNII-0JS9125PIZ (CAS 107444-51-9)
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