Droperidol Impurity 17 CAS 466118-73-0
| CAS No. | 466118-73-0 |
| Molecular Formula | C22H23N3O3 |
| Molecular Weight | 377.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Droperidol Impurity 17 (CAS 466118-73-0) is a certified pharmaceutical impurity reference standard with the molecular formula C22H23N3O3 and a molecular weight of 377.44 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Droperidol Impurity 17 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 377.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H23N3O3 |
| Molecular Weight | 377.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Droperidol Standards
- Droperidol EP Impurity B (CAS 1026015-45-1)
- Droperidol (CAS 548-73-2)
- Droperidol EP Impurity D (CAS 466118-75-2)
- Droperidol Impurity 10 (CAS CATO-C4X-276910)
- Droperidol Impurity 11 (CAS CATO-C4X-276911)
- Droperidol Impurity 19 (CAS CATO-C4X-276919)
- Droperidol Impurity 7 (CAS 60373-71-9)
- Droperidol Impurity 16 (CAS 39146-45-7)
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