Letrozole EP Impurity B CAS 113402-31-6
| CAS No. | 113402-31-6 |
| Molecular Formula | C22H13N3 |
| Molecular Weight | 319.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Letrozole EP Impurity B.
CATO supplies Letrozole EP Impurity B (CAS 113402-31-6), a pharmacopoeial impurity reference standard (molecular formula C22H13N3, MW 319.36 g/mol) used for the identification and quantification of trace impurities in APIs.
Letrozole EP Impurity B (C22H13N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Letrozole EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H13N3 |
| Molecular Weight | 319.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 3 |
Related Letrozole Standards
- Letrozole Impurity 21 (CAS CATO-C4X-182921)
- Letrozole Impurity 8 (CAS 2170106-13-3)
- Letrozole Impurity 12 (CAS CATO-C4X-182912)
- Letrozole Impurity 13 (CAS CATO-C4X-182913)
- Letrozole Impurity 7 (CAS 1644566-39-1)
- Letrozole Impurity 20 (CAS CATO-C4X-182920)
- Letrozole Impurity 10 (CAS CATO-C4X-182910)
- Letrozole Impurity 31 (CAS CATO-C4X-182931)
Recommended Standards
- Procaterol Impurity 49 (CAS CATO-C4X-181049)
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- Adenosine Impurity 9 (CAS 25775-85-3)
- Thioridazine Impurity 1 (CAS 7643-08-5)
- Roflumilast Impurity 4 (CAS 162401-30-1)
- Suzetrigine Impurity 35 (CAS CATO-C4X-336935)
- Disperse Blue 106 (CAS 68516-81-4)
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- N-Boc-7-fluoro-3,4-dihydroquinoline-4(2H)-one (CAS 1211594-21-6)
- [(2-chlorophenyl)methyl](cyclopropylmethyl)amine (CAS 1019506-73-0)
- 4-Methoxy-8-nitroquinoline (CAS 89770-28-5)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com