Edaravone impurity 03 CAS 114138-50-0
| CAS No. | 114138-50-0 |
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Edaravone impurity 03 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Edaravone impurity 03 (CAS 114138-50-0), a pharmacopoeial impurity reference standard (molecular formula C10H8N2O3, MW 204.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Edaravone impurity 03 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Edaravone Standards
- Edaravone impurity 1 (CAS 49597-17-3)
- Edaravone Impurity 28 (CAS 53855-47-3)
- Edaravone Impurity 18 (CAS 1016-41-7)
- Edaravone Impurity 22 (CAS 300543-31-1)
- Edaravone Impurity N3 (CAS 27301-70-8)
- Edaravone impurity 47 (CAS 53341-66-5)
- Edaravone Impurity 10 (CAS 710307-89-4)
- Edaravone Impurity 11 (CAS CATO-C4X-106211)
Recommended Standards
- 6,7-Dihydroxy-2-naphthoic acid (CAS 113458-95-0)
- 3-Hydroxy-4-phenyl-1H-pyrazole-5-carboxylic acid (CAS 1144488-84-5)
- 2-O-Ethyl-L-ascorbic Acid (CAS 112894-37-8)
- 3-(1-Benzofuran-2-yl)-2-oxopropanoic acid (CAS 1156724-77-4)
- Naproxen Impurity N3 (CAS 72337-73-6)
- Norepinephrine Impurity 80 (CAS CATO-C4X-151480)
- Salbutamol EP Impurity I(HCl) (CAS CATO-C4X-117636)
- Ethyl 2-amino-5-(pyridin-4-yl)thiazole-4-carboxylate (CAS 94284-72-7)
- 2-(3-Methylpyrazol-1-yl)ethanol 2-(3-methyl-1h-pyrazol-1-yl)ethanol 2-(3-methyl-pyrazol-1-yl)-ethanol 35000-51-2 (CAS 35000-51-2)
- (3-Methoxy-4-morpholinophenyl)boronic acid (CAS 1228182-92-0)
- 1-((tert-Butyldimethylsilyl)oxy)hex-5-en-3-ol (CAS 261633-45-8)
- H-Thr-Leu-OH (CAS 50299-12-2)
- 4-Methyl-5-[3-(2-pyridinyl)-6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl]-4H-1,2,4-triazole-3-thiol (CAS 551921-22-3)
- Vancomycin Hexapeptide (CAS 115236-65-2)
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