Edaravone Impurity 28 CAS 53855-47-3
| CAS No. | 53855-47-3 |
| Molecular Formula | C12H13NO2 |
| Molecular Weight | 203.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Edaravone Impurity 28 (CAS 53855-47-3, C12H13NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Edaravone Impurity 28 (C12H13NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 203.24 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Edaravone Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13NO2 |
| Molecular Weight | 203.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 1 |
Related Edaravone Standards
- Edaravone impurity 03 (CAS 114138-50-0)
- Edaravone impurity 1 (CAS 49597-17-3)
- Edaravone Impurity 18 (CAS 1016-41-7)
- Edaravone Impurity 22 (CAS 300543-31-1)
- Edaravone Impurity N3 (CAS 27301-70-8)
- Edaravone impurity 47 (CAS 53341-66-5)
- Edaravone Impurity 10 (CAS 710307-89-4)
- Edaravone Impurity 11 (CAS CATO-C4X-106211)
Recommended Standards
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- Ethyl 5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 312635-19-1)
- Anti-Inflammatory Peptide 2 (CAS 118850-72-9)
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