Articaine EP Impurity B CAS 114176-52-2
| CAS No. | 114176-52-2 |
| Molecular Formula | C12H18N2O3S |
| Molecular Weight | 270.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Articaine EP Impurity B (CAS 114176-52-2), a pharmacopoeial impurity reference standard (molecular formula C12H18N2O3S, MW 270.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Articaine EP Impurity B (C12H18N2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Articaine EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H18N2O3S |
| Molecular Weight | 270.35 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Articaine Standards
- Articaine Impurity 19 (CAS 2602451-78-3)
- Articaine EP Impurity A (CAS 1712677-79-6)
- Articaine Impurity C7 (CAS 23964-64-9)
- Articaine Impurity 11 (CAS 23964-56-9)
- Articaine (CAS 23964-58-1)
- Articaine EP Impurity E (CAS 1796888-45-3)
- Articaine Impurity C86 (CAS 2169099-30-1)
- Articaine impurity 01 (CAS 161448-93-7)
Recommended Standards
- Raloxifene Impurity 7 (CAS 63675-74-1)
- Cimetidine EP Impurity C (CAS 77076-18-7)
- Venetoclax Impurity 74 (CAS CATO-C4X-249574)
- Tolbutamide (CAS 64-77-7)
- Olaparib Impurity 67 (CAS 227609-85-0)
- Aztreonam Impurity 121 (CAS CATO-C4X-1522121)
- Vitamin Impurity 33 (CAS 6381-77-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com