Etravirine-D6 CAS 1142096-06-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1142096-06-7
Molecular Formula-
Molecular Weight441.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Etravirine-D6 CAS 1142096-06-7 chemical structure

Description

The occurrence of Etravirine-D6 is closely related to deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Etravirine-D6 (CAS 1142096-06-7), molecular formula C20H9D6BrN6O and molecular weight 441.31 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Etravirine-D6 (C20H9D6BrN6O) is characterized by deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Etravirine-D6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H9D6BrN6O
Molecular Weight441.31 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)19.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentBr-containing
Nitrogen Atoms6

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